At least 11 people are dead after a significant storm dumped a mixture of arctic air, snow and freezing, paralyzing cities in Texas, Oklahoma, Tennessee, Arkansas and Missouri, NBC News reported.

The dangerous storm is expected across parts of the U.S. Saturday from California to the Northeast as it continues to wreak havoc.

Rain, freezing temperatures and snow in areas from the "Golden State into the southern Rockies on Saturday," are expected, NBC News reported. The Midwest will receive a lighter dusting of the storm by Sunday. Temperatures as low as 27 degrees were expected in usually mild Las Vegas and surrounding areas, while New England was set to get the tail end by Monday.

The deaths, which include three in California and the mayor of a small Missouri town, were attributed to the deep freeze brought on by the winter storm, which cancelled hundreds of flights and left thousands of people without power.

The Santa Clara County, Calif. Sheriff's Office told NBC News hypothermia - abnormally low body temperature - had killed at least three people since cold weather conditions rolled in late Wednesday.

Deaths resulting from car crashes were attributed to the icy conditions stretching almost coast to coast.

In Missouri, Randall Arnall, mayor of Grandy, Mo. Died when his truck slid off icy State Route 97 and struck a tree Wednesday in Lawrence County.

A 16-year-old girl was killed on Wednesday when she lost control of her car on a slush-covered road a quarter-mile from her school in Lakeville, Minn., police said.

"The car slid sideways and was struck broadside by a vehicle traveling in the opposite direction," NBC News reported.

A 55-year-old man was killed when he was ejected from a car that lost control Wednesday on a highway near Sioux City, Iowa. He lost control after crossing a median of the highway that was 100-percent ice-covered, the vehicle was then struck by a freight truck traveling in the other direction, the Iowa State Patrol told NBC News.

A driver was killed when his car slammed into a truck Friday in Arlington, Texas, near Dallas, police said.

Other winter-related deaths included a 62-year-old man in Pope County, Ark. killed after an ice-coated tree fell on the camper that housed him. In Oklahoma City, a man was discovered dead under an overpass Wednesday in subfreezing temperatures.

In Carson City, Nev. the body of a man was found behind a convenience store Wednesday night after temperatures fell into the single digits, the coroner's office told NBC News.

Michael Palmer, a lead meteorologist for The Weather Channel, said a storm system was descending on the West Coast from Alaska, expected to dump snow on coastal Oregon and Northern California on Friday, and the Sierra Nevada range on Saturday. Then it will head to the Midwest on Sunday.