Mar 28, 2014 07:54 PM EDT By Russell Westerholm, UniversityHerald Reporter

Both the UConn Huskies (7) and Iowa State Cyclones (3) meet with an experienced squad in the Sweet 16, but with two different approaches.

UConn has held opponents to 63 points per game, but has sometimes struggled to hold down the more talented teams and also to put enough points up. Iowa State has averaged 83 points per game, but have struggled to stop even mediocre teams' offenses.

CLICK HERE to watch the game live.

While the game is technically in a neutral location, there are likely to be more Huskies fans than Cyclones fans in Madison Square Garden.

Napier was a freshman in 2011 when Jim Calhoun led Kemba Walker and company to a Big East title in the Garden and then to the national title. Now Kevin Ollie, Calhoun's handpicked successor, is trying to do the same with Napier, who says Walker has remained a mentor to him.

Trying to stop Melvin Ejim and the Cyclones' offense will be no easy task. With Ejim and DeAndre Kane, both long and talented scorers, UConn will need to get creative on defense as they would struggle to matchup man-to-man.

UConn has already pulled a surpising upset, beating former Big East rival Villanova, a two-seed in the second round of the NCAA Tournament.

"When we are at home games and we're tired, and they get us going, I don't think anybody on the court would be tired after that," Napier told reporters, according to the Associated Press. "Guys are just exerting all their energy that they possibly have and pushing themselves to get the game."

Iowa State will be without an offensive leader in Georges Niang, who broke his foot in the first game for the Cyclones. Still, Kane said he is confident in coach Fred Hoiberg's up-tempo approach to offense.

"Just letting us play free, giving us the confidence to go out there and play, play for each other," Kane told reporters, according to the AP.

See Now: Covert Team Inside Newsweek Revealed as Key Players in False Human Trafficking Lawsuit