Researchers have used historical data of human embryos to create a three-dimensional, interactive database that provides valuable insights into early human development. Due to modern limits on studying human embryos, current textbooks are usually based on old articles and information, often published more than 100 years ago. Independently verifying the historical information can be challenging. Here, Bernadette de Bakker analysed nearly 15,000 samples from the Carnegie Collection of human embryonic specimens, creating a three-dimensional digital atlas and database spanning the first two months of human development.The team identified and labelled about 150 organs and structures, establishing changes in the position of organs and clarifying current ambiguities. Using this new model, they identified consistent differences between human embryo development and that of mouse and chicken embryos, which are often used as models to study mammalian embryo development.
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